첼리돈산
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첼리돈산 속성
- 녹는점
- 265 °C (dec.) (lit.)
- 끓는 점
- 238.02°C (rough estimate)
- 밀도
- 1.4880 (rough estimate)
- 굴절률
- 1.5600 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: 1 mg/ml; DMSO:PBS (pH 7.2) (1:6): 0.14 mg/ml
- 물리적 상태
- Solid
- 산도 계수 (pKa)
- 1.26±0.40(Predicted)
- 색상
- Gray to brown
- 수용성
- 14.3g/L(25℃)
- Merck
- 13,2060
- BRN
- 163607
- InChIKey
- PBAYDYUZOSNJGU-UHFFFAOYSA-N
- LogP
- -0.746 (est)
- CAS 데이터베이스
- 99-32-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
첼리돈산 C화학적 특성, 용도, 생산
용도
Chelidonic acid is suitable for use a in homogeneous preparation of native dihydrodipicolinate synthase from pea. It may be used as endocyclic oxygen-containing ligand in the synthesis of aqua[bis(2-pyridylmethyl)amine][chelidonato(1.5-)]-copper(II) chelidonate(0.5-) monohydrate.일반 설명
Chelidonic acid (CA) is a γ-pyrone. It is reported as constituent of the rhizome of Chelidonium majus L. It has many pharmacological effects, such as mild analgesic and antimicrobial effects. Therapeutic potential of CA for the treatment of intestinal inflammation has been investigated. CA is reported as inhibitor of the rat brain glutamate decarboxylase. Biosynthesis of CA in cell suspension cultures of Leucojum aestivum has been studied.Purification Methods
The acid crystallises from aqueous EtOH. Dry it first at 100o/2hours, then at 160o to constant weight to remove water of crystallisation. It decarboxylates at 220-230o in a vacuum. [Riegel & Zwilgmeyer Org Synth Coll Vol II 126 1943, Beilstein 18 H 490, 18/8 V 646.]첼리돈산 준비 용품 및 원자재
원자재
준비 용품
첼리돈산 공급 업체
글로벌( 221)공급 업체
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