AR7
|
2物価
選択条件：
ブランド
- Sigma-Aldrich Japan
パッケージ
- 5mg
- 25mg
- 生産者Sigma-Aldrich Japan
- 製品番号SML0921
- 製品説明 ≥98% (HPLC)
- 英語製品説明AR7 ≥98% (HPLC)
- 包装単位5mg
- 価格￥22400
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番号SML0921
- 製品説明 ≥98% (HPLC)
- 英語製品説明AR7 ≥98% (HPLC)
- 包装単位25mg
- 価格￥72200
- 更新しました2024-03-01
- 購入
| 生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
|---|---|---|---|---|---|---|
| Sigma-Aldrich Japan | SML0921 | ≥98% (HPLC) AR7 ≥98% (HPLC) |
5mg | ￥22400 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | SML0921 | ≥98% (HPLC) AR7 ≥98% (HPLC) |
25mg | ￥72200 | 2024-03-01 | 購入 |
プロパティ
貯蔵温度 :Sealed in dry,2-8°C
溶解性 :DMSO: soluble20mg/mL, clear
外見 :powder
色 :white to beige
由来生物 :human
安定性： :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PUXHKTZKBDGXBB-UHFFFAOYSA-N
SMILES :Clc1cc2c(cc1)NC(=CO2)c3ccc(cc3)C
溶解性 :DMSO: soluble20mg/mL, clear
外見 :powder
色 :white to beige
由来生物 :human
安定性： :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PUXHKTZKBDGXBB-UHFFFAOYSA-N
SMILES :Clc1cc2c(cc1)NC(=CO2)c3ccc(cc3)C
安全情報
| 絵表示(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 注意喚起語: | Warning | ||||||||||||||
| 危険有害性情報: |
|
||||||||||||||
| 注意書き: |
|
説明
AR7 (80306-38-3) is an atypical retinoid which acts as an RARα antagonist and activates chaperone-mediated autophagy (CMA) via an RAR-dependent pathway.1 Downstream signaling results in an increase of LAMP-2A expression.1 Cells pretreated with AR7 had markedly improved viability in a paraquat-induced oxidative stress model.1 AR7 stimulated CMA and attenuated accumulation of SNCA oligomers in prolonged cultures of mutant cortical neurons2 indicating that CMA activation may be a viable disease modifying strategy in Parkinson’s disease3. A targetome analysis of AR7-induced CMA in cancer cells has been performed.4関連商品価格
- N-(3-Chlorophenyl)-N'-[5-[2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl]-2-thiazolyl]urea methanesulfonate (1:1)
￥76000-320000 - チゲサイクリン
￥9500-132300 - ボラセルチブ
￥11300-360000
供給者とメーカー
Shanghai Boyle Chemical Co., Ltd.
AdooQ BioScience, LLC
Bide Pharmatech Ltd.
AdooQ Bioscience CHINA
Shanghai Lollane Biological Technology Co.,Ltd.
Guangzhou Zhiya Chemdrugs Co.,Ltd
Shanghai EFE Biological Technology Co., Ltd.
Shanghai YuanYe Biotechnology Co., Ltd.
ShangHai Biochempartner Co.,Ltd
Shanghai Rechem science Co., Ltd.