379-68-0 Basic information More..
Product Name:18-HYDROXY-11-DEOXYCORTICOSTERONE
Synonyms:11-DEOXY-18-HYDROXYCORTICOSTERONE;18-HYDROXY-11-DEOXYCORTICOSTERONE;18-HYDROXYDEOXYCORTICOSTERONE;18-HYDROXY DOC;18,20-EPOXY-20,21-DIHYDROXY-4-PREGNEN-3-ONE;18,21-DIHYDROXY-4-PREGNENE-3,20-DIONE;4-PREGNENE-18,21-DIOL-3,20-DIONE;4-PREGNEN-18,21-DIOL-3,20-DIONE
CAS:379-68-0
MF:C21H30O4
MW:346.46
EINECS:2068343
Mol File:379-68-0.mol
379-68-0

Use

Recrystallise 18-hydroxy-11-deoxycorticosterone from Et2O/Me2CO to give crystals m 200-205o. When it is recrystallised from M2CO, it has m 191-195o. It has UV with max at 240nm. The 21-O-acetoxy-18-hydroxy derivative has m 158-159o (from Et2O/*C6H6), and the 21-O-acetoxy-18,20-epoxy derivative has m 149-154o (from Et2O). [Kahnt et al. Helv Chim Acta 38 1237 1955; Pappo J Am Chem Soc 81 1010 1959.]

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