670220-88-9 Basic information More..
Product Name:Crenolanib
Synonyms:Crenolanib, >=98%;Crenolanib;[1-[2-[5-(3-Methyloxetan-3-ylMethoxy)benziMidazol-1-yl]quinolin-8-yl]piperidin-4-yl]aMine;1-[2-[5-[(3-Methyl-3-oxetanyl)Methoxy]-1H-benziMidazol-1-yl]-8-quinolinyl]-4-piperidinaMine;ARO 002;CP 868596;Crenolanib (CP-868569);Crenolanib (CP-868596)
CAS:670220-88-9
MF:C26H29N5O2
MW:443.54
EINECS:
Mol File:670220-88-9.mol
670220-88-9

Use

Crenolanib (CP-868569) is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRα and PDGFRβ. Crenolanib (CP-868569) inhibits the activity of PDGFRα D842V kinase and prevented the phosphorylation of wild type PDGFRα. Crenolanib (CP-868569) possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation.

Crenolanib manufacturers

  • Crenolanib
  • US $53.00-132.00 / mg
  • 2026-04-21
  • CAS:670220-88-9
  • Min. Order:
  • Purity: 99.98%
  • Supply Ability: 10g
  • Crenolanib
  • US $7.00 / KG
  • 2019-07-06
  • CAS: 670220-88-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
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