313-04-2 Basic information More..
Product Name:DESMOSTEROL
Synonyms:3BETA-HYDROXY-5,24-CHOLESTADIENE;5,24-CHOLESTADIEN-3BETA-OL;24-DEHYDROCHOLESTEROL;DESMOSTEROL;Desmostero;Cholesta-5,24-dien-3beta-ol;Cholesta-5,24-dien-3-ol;Cholesta-5,24-dien-3-ol, (3beta)-
CAS:313-04-2
MF:C27H44O
MW:384.65
EINECS:206-236-2
Mol File:313-04-2.mol
313-04-2

Use

24-dehydro Cholesterol is an immediate precursor to cholesterol in the Bloch pathway of cholesterol biosynthesis. Structurally, it varies from cholesterol only by a single double bond at carbon 24 and has been used as cholesterol substitute in cellular membrane studies. During brain development, 24-dehydro cholesterol transiently accumulates, composing up to 30% of total brain sterol, where it is poised to rapidly enrich membrane sterols. However, defects in cholesterol synthesis can lead to a condition called, desmosterolosis, which results in an accumulation of excess 24-dehydro cholesterol. 24-dehydro Cholesterol has been reported to activate liver X receptor-target genes in both the liver of cholesterol-free mice and in cholesterol-starved macrophage foam cells in atherosclerotic lesions.[Cayman Chemical]

DESMOSTEROL manufacturers

  • DESMOSTEROL
  • US $0.00 / kg
  • 2025-12-01
  • CAS:313-04-2
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000KGS
  • Desmosterol
  • US $0.00-0.00 / kg
  • 2025-04-04
  • CAS:313-04-2
  • Min. Order: 1kg
  • Purity: 98%
  • Supply Ability: 1Ton
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