60-70-8 Basic information More..
Product Name:veratramine
Synonyms:veratramine;Vreaframine;(3b,23b)-14,15,16,17-Teradehydroveratraman-3,23-diol;NSC 17821;NSC 2388;Veratramine (NSC17821;Veratramine, >99%;Veratramine 60-70-8
CAS:60-70-8
MF:C27H39NO2
MW:409.6
EINECS:
Mol File:60-70-8.mol
60-70-8

Use

The hedgehog (Hh) signaling pathway, which is blocked by cyclopamine , plays a key role in morphogenesis and has potential applications in the treatment of cancer. Veratramine, a teratogenic steroidal alkaloid isolated from the corn lily (Veratrum sp.), is an analog of cyclopamine that can inhibit the Hh signaling-dependent proliferation of NIH/3T3 cells at 8 μM. Additionally, veratramine has anti-thrombotic activity as it dose dependently inhibits platelet aggregation in rabbits ex vivo. While it may be most useful as a signal transduction inhibitor for treating tumors, veratramine also induces serotonin release and inhibits its re-uptake in the CNS.

veratramine manufacturers

  • veratramine
  • US $0.00 / MG
  • 2026-04-17
  • CAS:60-70-8
  • Min. Order: 10MG
  • Purity: 98% HPLC
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  • Veratramine
  • US $0.00 / mg
  • 2023-02-24
  • CAS:60-70-8
  • Min. Order: 5mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 10 g
  • Veratramine 60-70-8
  • US $45.00 / g
  • 2022-02-14
  • CAS:60-70-8
  • Min. Order: 10mg
  • Purity: ≥98% HPLC
  • Supply Ability: 1000.00 kgs
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