518-28-5 Basic information More..
Product Name:Podophyllotoxin
Synonyms:Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)-, (5R,5aR,8aR,9R)-;Podophyllotoxin ,98%;(5R)-5,8,8aβ,9-Tetrahydro-9β-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aαH)-one;Podophyllotoxin,95%;trimethoxyphenyl)-furo(3',4':6,7)naphtho[2,3-d]-1,3-dioxol-6(5aH)-one;PODOPHYLLIN(RG);5,8,8a,9-tetrahydro-9-hydroxy-5- (3,4,5-trimethoxyphenyl)-furo(3',4':6,7)naphtho(2,3-d)-1,3-dioxol-6(5ah)-one;(5R,5AR,8AR,9R)-9-HYDROXY-5-(3,4,5-TRIMETHOXY-PHENYL)-5,8,8A,9-TETRAHYDRO-5AH-FURO[3',4':6,7]NAPHTHO[2,3-D][1,3]DIOXOL-6-ONE
CAS:518-28-5
MF:C22H22O8
MW:414.41
EINECS:208-250-4
Mol File:518-28-5.mol
518-28-5

Use

Podophyllotoxin is a non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum species. It binds to topoisomerase II during the late S and early G2 stage, blocking tubulin polymerization and, thus, inhibiting mitosis. In addition to being used as a cathartic, purgative, antiviral agent, vesicant, and antihelminthic, podophyllotoxin is the starting material for the semi-synthesis of the anti-cancer drugs etoposide , teniposide , and etopophos.

Podophyllotoxin manufacturers

  • Podophyllotoxin
  • US $150.00 / kg
  • 2025-05-21
  • CAS:518-28-5
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 500kg
  • Podofilox
  • US $29.00 / mL
  • 2025-05-20
  • CAS:518-28-5
  • Min. Order:
  • Purity: 99.07%
  • Supply Ability: 10g
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