3521-62-8 Basic information More..
Product Name:Erythromycin Estolate
Synonyms:eritroger;eromycin;erythromycin,propionate(ester),compd.withmonododecylsulfate(1:1);erythromycin5-(3-propionate)dodecylsulfate;erythromycinpropionate,compd.withdodecylsulfate;erythromycinpropionatelaurylsulfate;ERYTHROMYCIN ESTOLATE;ERYTHROMYCIN 2'-PROPANOATE DODECYL SULFATE SALT
CAS:3521-62-8
MF:C52H97NO18S
MW:1056.39
EINECS:222-532-4
Mol File:3521-62-8.mol
3521-62-8

Use

Erythromycin estolate, erythromycin propionate lauryl sulfate(Ilosone), is the lauryl sulfate salt of the 2'-propionateester of erythromycin. Erythromycin estolate is acid stableand absorbed as the propionate ester. The ester undergoesslow hydrolysis in vivo. Only the free base binds to bacterialribosomes. Some evidence, however, suggests that theester is taken up by bacterial cells more rapidly than thefree base and undergoes hydrolysis by bacterial esteraseswithin the cells. The incidence of cholestatic hepatitis is reportedlyhigher with the estolate than with other erythromycinpreparations.Erythromycin estolate occurs as long needles that aresparingly soluble in water but soluble in organic solvents. administration for the treatment of serious infections,such as Legionnaires disease, or when oral administrationis not possible. Solutions are stable for 1 week whenrefrigerated.

Erythromycin Estolate manufacturers

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Company Name: Shaanxi Dideu Medichem Co. Ltd      Recommend     Complaint
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Products Intro: Product Name:Erythromycin 2'-propionate dodecyl sulfate
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Purity:0.97 Package:mgs,gs,kgs Remarks:A822654
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