| | 536-33-4 Basic information More.. |
| Product Name: | Ethionamide | | Synonyms: | 1314 TH;1314 TN;1314th;2-Ethyl-4-thioamidylpyridine;2-Ethyl-4-thiocarbamoylpyridine;2-Ethylisonicotinic acid thioamide;2-Ethylisonicotinic thioamide;2-ethylisonicotinicacidthioamide | | CAS: | 536-33-4 | | MF: | C8H10N2S | | MW: | 166.24 | | EINECS: | 208-628-9 | | Mol File: | 536-33-4.mol |  |
Use
2-Ethylthioisonicotinamide (Trecator SC) occurs as a yellowcrystalline material that is sparingly soluble in water. Thisnicotinamide has weak bacteriostatic activity in vitro but, becauseof its lipid solubility, is effective in vivo. In contrast tothe isoniazid series, 2-substitution enhances activity in thethioisonicotinamide series.Ethionamide is rapidly and completely absorbed followingoral administration. It is widely distributed throughoutthe body and extensively metabolized to predominantly inactiveforms that are excreted in the urine. Less than 1% ofthe parent drug appears in the urine.Ethionamide is considered a secondary drug for the treatmentof tuberculosis. It is used in the treatment of isoniazidresistanttuberculosis or when the patient is intolerant toisoniazid and other drugs. Because of its low potency, thehighest tolerated dose of ethionamide is usually recommended.Gastrointestinal intolerance is the most commonside effect associated with its use. Visual disturbances andhepatotoxicity have also been reported.
- Ethionamide
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- 2026-09-20
- CAS:536-33-4
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 20 tons
- Ethionamide
-
- $50.00
- 2026-07-27
- CAS:536-33-4
- Purity: 99.92%
- Supply Ability: 10g
- Ethionamide
-
- $50.00
- 2026-07-27
- CAS:536-33-4
- Purity: 99.92%
- Supply Ability: 10g
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536-33-4
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