121679-13-8 Basic information More..
Product Name:Naratriptan
Synonyms:Naratriptan;Naratriptane;N-methyl-2-[3-(1-methyl-4-piperidyl)-1H-indol-5-yl]ethanesulfonamide;Naratriptan(Amerge);N-Methyl-2-[3-(1-methylpiperidin-4-yl)-1H-indol-5-yl]ethanesulfonamide;Naratriptan1;AMERGE; NARAMIG; GR-85548A;N-methyl-3-(1-methyl-4-piperidinyl)-1H-Indole-5-ethanesulfonamide
CAS:121679-13-8
MF:C17H25N3O2S
MW:335.46
EINECS:
Mol File:121679-13-8.mol
121679-13-8

Use

Naratriptan, the third triptan approved in 1998, is one of themost lipophilic triptans marketed to date. It has a much improvedbioavailability (63% in men and 74% in women), agreater affinity for 5-HT1B/1D receptors (3–6 times), and alower recurrence rate than sumatriptan because of its muchlonger elimination half-life. Naratritan also has a favorableCNS side effect profile when compared with sumatriptanor zolmitriptan because of its metabolic stability,thereby lacking a N-demethylated active metabolite and asignificant renal excretion ( 70% of naratriptan is excretedunchanged and the rest of the administered dose is degradedvia several CYP isozymes).

Naratriptan manufacturers

  • Naratriptan
  • US $35.00-70.00 / mg
  • 2025-09-03
  • CAS:121679-13-8
  • Min. Order:
  • Purity: 99.08%
  • Supply Ability: 10g
  • Naratriptan
  • US $16.00 / KG
  • 2024-01-18
  • CAS:121679-13-8
  • Min. Order: 1KG
  • Purity: 99.90%
  • Supply Ability: 20T
  • Naratriptan
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:121679-13-8
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
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Products Intro: Product Name:N-methyl-3-(1-methyl-4-piperidinyl)-1H-Indole-5-ethanesulfonamide
CAS:121679-13-8
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