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Product Name:OSI-420
Synonyms:Ethanol, 2-[[4-[(3-ethynylphenyl)aMino]-7-(2-Methoxyethoxy)-6-quinazolinyl]oxy]-, hydrochloride;OSI-420 (DesMethyl Erlotinib,CP-473420);CP-473420;DesMethyl Erlotinib;OSI-420 hydrochloride;OSI-420 (DesMethyl Erlotinib);Erlotinib O-DesMethyl Metabolite IsoMer (M14) HCl;6-O-Desmethyl Erlotinib 2
CAS:183320-51-6
MF:C21H22ClN3O4
MW:415.87
EINECS:200-258-5
Mol File:183320-51-6.mol
183320-51-6

Use

OSI-420 (Desmethyl Erlotinib,CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells.

OSI-420 manufacturers

  • OSI-420
  • US $1.00 / g
  • 2020-01-13
  • CAS:183320-51-6
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 1ton
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