14277-97-5 Basic information More..
Product Name:DOMOIC ACID
Synonyms:(2S,3S,4S)-4-[(2Z,4E,6R)-6-carboxyhepta-2,4-dien-2-yl]-3-(carboxymethyl)pyrrolidine-2-carboxylic acid;Domoic Acid, Mytilus edulis - CAS 14277-97-5 - Calbiochem;3-Pyrrolidineacetic acid, 2-carboxy-4-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadien-1-yl]-, (2S,3S,4S)-;(2S-(2-alpha,3-beta,4-beta(1Z,3E,5S*)))-2-Carboxy-4-(5-carboxy-1-methyl-1,3-hexadienyl)-3-pyrrolidineacetic acid;(-)-Domic acid;(2S)-2α-Carboxy-4β-[(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadienyl]-3β-pyrrolidineacetic acid;L-Domic acid;3-Pyrrolidineacetic acid, 2-carboxy-4-(1Z,3E,5R)-5-carboxy-1-methyl-1,3-hexadienyl-
CAS:14277-97-5
MF:C15H21NO6
MW:311.33
EINECS:
Mol File:14277-97-5.mol
14277-97-5

Use

Domoic acid (~300 mg) is purifed on a Dowex1 column (3.5 x 40 mm, 200-400 mesh, acetate form), washed with H2O until neutral, then eluted with increasing concentrations of AcOH (8L) from 0 to 0.25M. The fraction containing domoic acid (in 50mL) is collected, evaporated to dryness under reduced pressure and recrystallised from aqueous EtOH. It is a glutamate and a Kainate receptor agonist. [Impellizzeri et al. Phytochemistry 14 1549 1975, Takemoto & Diago Arch Pharm 293 627 1960, Beilstein 22/4 V 371.]

DOMOIC ACID manufacturers

  • Domoic acid
  • 2026-05-11
  • CAS:14277-97-5
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  • Supply Ability: 10g
  • DOMOIC ACID
  • 2025-12-01
  • CAS:14277-97-5
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000KGS
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