| | 600-15-7 Basic information More.. |
| Product Name: | DL-2-Hydroxybutyric Acid | | Synonyms: | dl-2-hydroxy-n-butyricacid(alpha-)(containspolymolecular);(±)-2-hydroxybutyric acid;DL-2-Hydroxybutyric Acid (contains Polymolecular esterification product);rac-(2R*)-2-Hydroxybutyric acid;DL-alpha-Hydroxybutyric acid;NSC 6495;(contains PolyMolecular esterification product);DL-2-Hydroxybutyric Acid  | | CAS: | 600-15-7 | | MF: | C4H8O3 | | MW: | 104.1 | | EINECS: | 209-985-3 | | Mol File: | 600-15-7.mol |  |
Use
2-Hydroxybutyric acid (or alpha - hydroxy butyrate) is a hydroxy butyric acid with the hydroxyl group on the carbon adjacent to the carboxyl. It is a chiral compound having two enantiomers, D-2- hydroxybutyric acid and L-2-hydroxybutyric acid. 2-Hydroxy butyrate, the conjugate base of 2-hydroxy butyric acid, is produced in mammalian tissues (principally hepatic) that catabolize L-threonine or synthesize glutathione. Oxidative stress or detoxification demands can dramatically increase the rate of hepatic glutathione synthesis. Under such metabolic stress conditions, supplies of L-cysteine for glutathione synthesis become limiting, so homocysteine is diverted from the transmethylation pathway forming methionine into the transsulfuration pathway forming cystathionine. 2-Hydroxybutyrate is released as a byproduct when cystathionine is cleaved to cysteine that is incorporated into glutathione. Chronic shifts in the rate of glutathione synthesis may be reflected by urinary excretion of 2-hydroxybutyrate.
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600-15-7
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