37661-08-8 Basic information More..
Product Name:BACAMPICILLIN HYDROCHLORIDE
Synonyms:ambacamp;ambaxin;bacacil;bapc;becampicillin;o)-3,3-dimethyl-7-oxo-,1-((ethoxycarbonyl)oxy)ethylester,hydrochloride;penglobe;BACAMPICILLIN HYDROCHLORIDE
CAS:37661-08-8
MF:C21H28ClN3O7S
MW:501.98
EINECS:253-580-4
Mol File:37661-08-8.mol
37661-08-8

Use

Bacampicillin hydrochloride (Spectrobid) is the hydrochloridesalt of the 1-ethoxycarbonyloxyethyl ester of ampicillin.It is a prodrug of ampicillin with no antibacterial activity.After oral absorption, bacampicillin is hydrolyzed rapidly byesterases in the plasma to form ampicillin.Oral absorption of bacampicillin is more rapid and completethan that of ampicillin and less affected by food.Plasma levels of ampicillin from oral bacampicillin exceedthose of oral ampicillin or amoxicillin for the first 2.5 hoursbut thereafter are the same as for ampicillin and amoxicillin.49 Effective plasma levels are sustained for 12 hours,allowing twice-a-day dosing.

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