| | 211427-08-6 Basic information More.. |
| Product Name: | Diquafosol Tetrasodium | | Synonyms: | INS 365;D03864;Diquafosol sodium;Diquafosol sodium (jan);Diquafosol tetrasodium;Diquafosol tetrasodium (usan);Diquafosol Impurity 7(UP4U);[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate | | CAS: | 211427-08-6 | | MF: | C18H27N4NaO23P4 | | MW: | 814.3 | | EINECS: | 253-874-2 | | Mol File: | 211427-08-6.mol |  |
Use
Diquafosol (INS-365) was approved in Japan in 2010 as a 3%
ophthalmic solution for treatment of dry eye disease. Clinical diagnosis of dry eye is difficult because the condition
presents a variety of symptoms. Treatment options include tear
supplements (lubricants), anti-inflammatory drugs (e.g., cyclosporine
eye drops or steroid eye drops), and tear retention devices. Diquafosol
is a unique agent for the treatment of dry eye in that it acts as a P2Y2
purinergic receptor agonist with the ability to activate this receptor on
the ocular surface and stimulate water, lipid, and mucin secretion. Diquafosol is metabolized by phosphodiesterases to UTP, UDP, UMP, and uridine. Diquafosol has been well tolerated in clinical trials, with side effects being local to the ocular surface.In addition,no serious ocular or systemic adverse drug reactions were found
during the clinical trials.
- Diquafosol Sodium
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- US $0.00 / KG
- 2025-09-03
- CAS:211427-08-6
- Min. Order: 1KG
- Purity: 99%min
- Supply Ability: 10kg
- Diquafosol Impurity 11
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- US $0.00-0.00 / mg
- 2025-08-27
- CAS:211427-08-6
- Min. Order: 5mg
- Purity: 95%+
- Supply Ability: 1000mg
- Diquafosol Impurity 11
-
- US $0.00 / mg
- 2024-04-11
- CAS:211427-08-6
- Min. Order: 1mg
- Purity: 99.88%
- Supply Ability: 50mg
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211427-08-6
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| Products Intro: |
Product Name:tetrasodium;[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl] [[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] phosphate
CAS:211427-08-6
Purity:98% Package:1g,10g,25g,100g,500g,1kg |
| CB Index: |
58 |
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