60-32-2 Basic information More..
Product Name:6-Aminocaproic acid
Synonyms:177 J.D;177 J.D.;177j.d.;177jd;Acepramin;Acepramine;Afibrin;Amicar
CAS:60-32-2
MF:C6H13NO2
MW:131.17
EINECS:200-469-3
Mol File:60-32-2.mol
60-32-2

Use

6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.

6-Aminocaproic acid manufacturers

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