128794-94-5 Basic information More..
Product Name:Mycophenolate mofetil
Synonyms:2-morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoate;2-morpholinoethyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoate;6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-m;(4E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic acid 2-morpholin-4-ylethyl ester;Linfonex;2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate;(E)-2-Morpholinoethyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-m;2-morpholin-4-ylethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1h-isobenzofuran-5-yl)-4-methyl-hex-4-enoate
CAS:128794-94-5
MF:C23H31NO7
MW:433.49
EINECS:
Mol File:128794-94-5.mol
128794-94-5

Use

Mycophenolate mofetil was launched in 1995 in the U.S.A., its first market worldwide, for the prevention of acute kidney transplant rejection in conjunction with other immunosuppressive therapy and to treat refractory acute kidney graft rejection. With improved oral absorption and bioavailability, mycophenolate mofetil is a prodrug of mycophenolic acid (MPA), a fermentation product of several Penicillium species. MPA is a selective, reversible, non-competitive inhibitor of inosinate dehydrogenase and guanylate synthetase. It inhibits the de now pathway of purine biosynthesis. MPA was found to have more potent antiproliferative effects on T and B lymphocytes than other cell types. Compared with other immunosuppressants, mycophenolate mofetil is reportedly superior due to its unique mechanism of action and excellent safety profile for long term use. Mycophenolate mofetil is being investigated clinically in the treatment of heart and liver transplantation rejection, asthma, in preventing coronary artery restenosis, and in treating rheumatoid arthritis.

Mycophenolate mofetil manufacturers

  • Mycophenolate Mofetil
  • US $98.00-47.00 / mg
  • 2025-05-17
  • CAS:128794-94-5
  • Min. Order:
  • Purity: 99.85%
  • Supply Ability: 10g
  • Mycophenolate mofetil
  • US $0.00 / kg
  • 2025-05-12
  • CAS:128794-94-5
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000KGS
  • Mycophenolate mofetil
  • US $120.00 / KG
  • 2025-03-21
  • CAS:128794-94-5
  • Min. Order: 1KG
  • Purity: 99.99%
  • Supply Ability: 100KG
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