| | 7252-83-7 Basic information More.. |
| Product Name: | Bromoacetaldehyde dimethyl acetal | | Synonyms: | Ethane,2-broMo-1,1-diMethoxy-;2-BroMo-1,1-diMethoxyethane, 98%+;2-Bromo-1,1-dimethoxyethane
2,2-Dimethoxyethyl Bromide;2 - broMine - 1, 1 - diMethoxy ethane;BROMOACETALDEHYDE DIMETHYL ACETAL (BADA);Bromoacetaldehyde dimethyl acetal, 97+%, stab. with potassium carbonate;Bromoacetaldehyde Dimethyl Acetal (stabilized with K2CO3);Bromoacetoaldehyde dimethyl acetal ,98% | | CAS: | 7252-83-7 | | MF: | C4H9BrO2 | | MW: | 169.02 | | EINECS: | 230-669-6 | | Mol File: | 7252-83-7.mol |  |
Use
2-Bromo-1,1-dimethoxyethane (Bromoacetaldehyde dimethyl acetal) is used in the synthesis of 2,3-O-acetal via reaction with 2,3-diol in the presence of 10-camphorsulphonic acid (CSA). 2-bromo-1,1-dimethoxyethane was used to react with 4-hydroxylbenzaldehyde, and finally aldehyde substituted prodrug was generated by TFA-mediated deacetalization. It is widely used in chemistry for the synthesis of a variety of antibiotics (including erythromycin and cephalosporins) and other drugs. It is an important and highly reactive bifunctional compound with a good leaving group and a masked aldehyde function. It can be used as a starting material in a variety of reactions to provide N-alkylated compounds, lactams, aldehydes, oximes, azides, and acyclic di-/polyselenides.
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7252-83-7
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