5104-49-4 Basic information More..
Product Name:Flurbiprofen
Synonyms:1’-biphenyl)-4-aceticacid,2-fluoro-alpha-methyl-(;1’-biphenyl]-4-aceticacid,2-fluoro-alpha-methyl-[;2-(2-Fluoro-4-biphenyl)propionicacid;2-(2-fluoro-4-biphenylyl)propionicacid;2-fluoro-alpha-methyl-4-biphenylaceticaci;(+/-)-FLURBIPROFEN;FLURBIPROFEN;ANSAID
CAS:5104-49-4
MF:C15H13FO2
MW:244.26
EINECS:225-827-6
Mol File:5104-49-4.mol
5104-49-4

Use

Flurbiprofen (Ansaid, Ocufen, Froben), is another drug inthis class indicated for both acute and long-term managementof RA and OA but with a more complex mechanism ofaction. Unlike the other drugs in this class, it does not undergochiral inversion (i.e., the conversion of the “inactive”[R]-enantiomer to the active, [S]-enantiomer). Similar to aspirinand other salicylates, both flurbiprofen enantiomersblock COX-2 induction as well as inhibiting the nuclearfactor-κB-mediated polymorphonuclear leukocyte apoptosissignaling; therefore, both enantiomers are believed to contributeequally to its overall anti-inflammatory action.(R)-flurbiprofen is actually a strong clinical candidate forthe treatment of Alzheimer disease, because it has beenshown to reduce Aβ42 production by human cells.

Flurbiprofen manufacturers

  • Flurbiprofen
  • US $0.00-0.00 / Kg/Drum
  • 2025-08-01
  • CAS:5104-49-4
  • Min. Order: 1KG
  • Purity: 99%-100.5%; BP
  • Supply Ability: 500 KGS
  • (R)-2-Flurbiprofen
  • US $5.00-0.50 / KG
  • 2025-08-01
  • CAS:5104-49-4
  • Min. Order: 1KG
  • Purity: 99% hplc
  • Supply Ability: 500TONS
  • Flurbiprofen
  • US $50.00-72.00 / mg
  • 2025-07-15
  • CAS:5104-49-4
  • Min. Order:
  • Purity: 99.96%
  • Supply Ability: 10g
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