6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE
| | 545380-34-5 Basic information More.. |
| Product Name: | 6-AMINO-4-(4-PHENOXYPHENYLETHYLAMINO)QUINAZOLINE | | Synonyms: | EVP4593; EVP 4593; EVP-4593;CS-902;NF-κB Activation Inhibitor - CAS 545380-34-5 - Calbiochem;QNZ;EVP 4593;EVP4593;EVP-4593;4,6-Quinazolinediamine, N4-[2-(4-phenoxyphenyl)ethyl]- | | CAS: | 545380-34-5 | | MF: | C22H20N4O | | MW: | 356.42 | | EINECS: | | | Mol File: | 545380-34-5.mol |  |
Use
QNZ is a novel inhibitor of NFkB which displays potent inhibitory effects on both NFKB transcriptional activation (IC50=11nM) and TNF-α production (IC50=7nM). It dose-dependently inhibited carragenin-induced edema formation in the rat paw model (1mg/Kg). A useful tool to explore the role of NFkB in cellular signaling pathways.
- QNZ
-
- US $36.00-85.00 / mg
- 2025-10-26
- CAS:545380-34-5
- Min. Order:
- Purity: 99.86%
- Supply Ability: 10g
|
|
545380-34-5
Recommend Suppliers |
|
| Tag:
545380-34-5
|