55268-75-2 Basic information More..
Product Name:Cefuroxime
Synonyms:Cefuroxime VETRANAL;5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(aminocarbonyl)oxymethyl-7-(2Z)-2-furanyl(methoxyimino)acetylamino-8-oxo-, (6R,7R)-;5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[[(aminocarbonyl)oxy]methyl]-7-[[2-furanyl(methoxyimino)acetyl]amino]-8-oxo-, [6R-[6α,7β(Z)]]-;Biofuroksym;Cephuroxime;Ketocef;(6r-(6-alpha,7-beta(zethyl)-7-((2- furanyl(methyoxyimino)acetyl)amino)-8-oxo-;Cefuroxime
CAS:55268-75-2
MF:C16H16N4O8S
MW:424.39
EINECS:259-560-1
Mol File:55268-75-2.mol
55268-75-2

Use

Cefuroxime axetil (Ceftin) is the 1-acetyoxyethyl ester ofcefuroxime. During absorption, this acid-stable, lipophilic,oral prodrug derivative of cefuroxime is hydrolyzed to cefuroximeby intestinal and/or plasma enzymes. The axetilester provides an oral bioavailability of 35% to 50% of cefuroxime,depending on conditions. Oral absorption of theester is increased by food but decreased by antacids and histamineH2-antagonists. The latter effect may be because ofspontaneous hydrolysis of the ester in the intestine becauseof the higher pH created by these drugs. Axetil is used forthe oral treatment of non–life-threatening infections causedby bacteria that are susceptible to cefuroxime. The prodrugform permits twice-a-day dosing for such infections.

Cefuroxime manufacturers

  • Cefuroxime
  • 2025-08-10
  • CAS:55268-75-2
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  • Purity: 0.99
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  • Cefuroxime
  • US $0.00-0.00 / Kg/Drum
  • 2025-08-08
  • CAS:55268-75-2
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 500kg
  • Cefuroxim
  • US $0.00 / KG
  • 2025-08-08
  • CAS:55268-75-2
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
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