| | 4070-80-8 Basic information More.. |
| Product Name: | Sodium Stearyl Fumarate | | Synonyms: | SODIUM STEARYL FUMARATE;sodium octadecyl fumarate;SodiumStearylFumarate(Excipient)OpenPartDmf;Sodium Stearyl Fumarate (Excipient);Monosodium stearyl fumarate;2-Butenedioic acid (2E)-, monooctadecyl ester, sodium salt;SODIUMSTEARYLFUMARATE,FCC;SODIUMSTEARYLFUMARATE,NF | | CAS: | 4070-80-8 | | MF: | C22H41NaO4 | | MW: | 392.56 | | EINECS: | 223-781-1 | | Mol File: | 4070-80-8.mol |  |
Use
Sodium stearyl fumarate is used in oral pharmaceutical formulations
and is generally regarded as a nontoxic and nonirritant
material.
Metabolic studies of sodium stearyl fumarate in the rat and dog
indicated that approximately 80% was absorbed and 35% was
rapidly metabolized. The fraction absorbed was hydrolyzed to stearyl alcohol and fumaric acid, with the stearyl alcohol further
oxidized to stearic acid. In the dog, sodium stearyl fumarate that
was not absorbed was excreted unchanged in the feces within 24
hours.
Stearyl alcohol and stearic acid are naturally occurring
constituents in various food products, while fumaric acid is a
normal constituent of body tissue. Stearates and stearyl citrate have
been reviewed by the WHO and an acceptable daily intake for
stearyl citrate has been set at up to 50 mg/kg body-weight. The
establishment of an acceptable daily intake for stearates and
fumaric acid was thought unnecessary.
Disodium fumarate has been reported to have a toxicity not
greatly exceeding that of sodium chloride.
- Sodium Stearyl Fumarate
-
- US $0.00-0.00 / kg
- 2025-08-13
- CAS:4070-80-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20MT
- Sodium Stearyl Fumarate
-
- US $0.00 / Kg/Drum
- 2025-08-13
- CAS:4070-80-8
- Min. Order: 1KG
- Purity: 99%-101.5%;USP-NF
- Supply Ability: 1000kgs
- Sodium Stearyl Fumarate
-
- US $0.00 / KG
- 2025-08-08
- CAS:4070-80-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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4070-80-8
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