| | 1439399-58-2 Basic information More.. |
| Product Name: | CB-839 | | Synonyms: | 2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol-2-yl)acetamide CB-839;2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol-2-yl)acetamide;CPD1593;CB-839;N-[5-[4-[6-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]-3-pyridazinyl]butyl]-1,3,4-thiadiazol-2-yl]-2-pyridineacetamide;CB839 ;CB 839 ;CB-839;GLS1 Inhibitor III, CB-839 - CAS 1439399-58-2 - Calbiochem;CB-839,TELAGLENASTAT | | CAS: | 1439399-58-2 | | MF: | C26H24F3N7O3S | | MW: | 571.57 | | EINECS: | | | Mol File: | 1439399-58-2.mol |  |
Use
In the mouse TNBC model, single agent CB-839 (200 mg/kg, p.o.) suppresses tumor growth by 61% relative to vehicle control. In the mouse JIMT-1 xenograft model, CB-839 alone (200 mg/kg, p.o.) results in 54% tumor growth inhibition (TGI) relative to vehicle control, combination of CB-839 (200 mg/kg, p.o.) with paclitaxel (10 mg/kg, p.o.) largely suppresses the regrowth of the tumors resulting in a TGI relative to vehicle control of 100%.
- Telaglenastat
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- US $32.00-72.00 / mg
- 2025-05-24
- CAS:1439399-58-2
- Min. Order:
- Purity: 99.89%
- Supply Ability: 10g
- CB-839
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- US $0.00-0.00 / KG
- 2025-04-04
- CAS:1439399-58-2
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1Ton
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1439399-58-2
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