| | 302-22-7 Basic information More.. |
| Product Name: | Chlormadinone acetate | | Synonyms: | Clormadinoneacetate;17α-acetoxy-6-chloro-4,6-pregnadiene-3,20-dione;chloromadinone 17-acetate;6-Chloro-17-acetoxy-4,6-pregnadiene-3,20-dione;17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione, 6-Chloro-6-dehydro-17α-acetoxyprogesterone, Gestafortin, Matrol, Menstridyl, 6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate;17-alpha-acetoxy-;Chlormadinone acetate,17α-Acetoxy-6-chloro-4,6-pregnadiene-3,20-dione, 6-Chloro-17α-hydroxy-4,6-pregnadiene-3,20-dione 17-acetate, 6-Chloro-6-dehydro-17α-acetoxyprogesterone, Gestafortin, Matrol, Mens;(8R,9S,10R,13S,14S,17R)-17-acetyl-6-chloro-10,13-diMethyl-3-oxo-2,3,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate | | CAS: | 302-22-7 | | MF: | C23H29ClO4 | | MW: | 404.93 | | EINECS: | 206-118-0 | | Mol File: | 302-22-7.mol |  |
Use
Chlormadinone acetate, a synthetic progestogen, was introduced
in 1965 as a component in oral contraceptive preparations. In 1967, as a result of
new regulations required by the United States Food and Drug Administration,
chlormadinone acetate was submitted to long-term toxicity studies and by the early
1970s it was shown to be associated with an increased incidence of mammary
tumours in beagle bitches which led to its withdrawal by several regulatory
authorities. Subsequently the validity of the beagle bitch model as a predictor of
carcinogenicity of steroid contraceptives has been contested by many national
regulatory authorities and chlormadinone remains available in some countries for
contraceptive purposes. In some instances it is indicated for treatment of
progesterone deficiency and endometriosis, and of irregular uterine bleeding due
to fibroids.
(Reference: (WHODI) WHO Drug Information, 84.1, 5, 1984)
- Chlormadinone acetate
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- US $0.00-0.00 / KG
- 2025-07-02
- CAS:302-22-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 5000
- Chlormadinone acetate
-
- US $37.00 / mg
- 2025-06-17
- CAS:302-22-7
- Min. Order:
- Purity: 98.97%
- Supply Ability: 10g
- Chlormadinone acetate
-
- US $0.00 / KG
- 2025-05-16
- CAS:302-22-7
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
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302-22-7
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