Use
Allyl chloride is toxic and flammable. Exposures to allyl chloride cause a cough, sore throat,
headache, dizziness, weakness, respiratory distress, abdominal pain, burning sensation,
vomiting, and loss of consciousness. After acute inhalation exposures to high levels of
allyl chloride, workers developed irritation of the eyes and respiratory passages, loss of
consciousness, and fatal injury. Prolonged and intense exposure produced conjunctivitis,
reddening of eyelids, and corneal burn, damage to the CNS, causing motor and sensory
neurotoxic damage, and the heart and respiratory system, causing the onset of pulmonary
edema in humans. Laboratory rabbits exposed to allyl chloride through inhalation developed
degenerative changes that included dilation of sinusoids and vacuolar degeneration
in the liver, congestion or cloudy swelling and fatty degeneration of the epithelium of the
renal convoluted tubules, and thickening of the alveolar septa in the lungs. The exposed cat
exhibited only muscle weakness and unsteady gait toward the end of the exposure period.