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| | NZ-419,5-hydroxy-1-methylimidazolidine-2,4-dione Basic information |
| | NZ-419,5-hydroxy-1-methylimidazolidine-2,4-dione Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | form | Solid | | color | White to off-white | | Optical Rotation | -1.3816°(C=1.0025g/100ml MEOH) |
| | NZ-419,5-hydroxy-1-methylimidazolidine-2,4-dione Usage And Synthesis |
| Uses | NZ 419 (5-Hydroxy-1-methylhydantoin) is a metabolite of creatinine and an antioxidant with oral activity, which has the ability to scavenge hydroxyl radicals (OH). NZ 419 can inhibit the progression of chronic kidney disease (CKD) in rats[1]. | | References | [1] Ienaga K, et al. Creatinine and HMH (5-hydroxy-1-methylhydantoin, NZ-419) as intrinsic hydroxyl radical scavengers. Drug Discov Ther. 2011;5(4):162-175. DOI:10.5582/ddt.2011.v5.4.162 |
| | NZ-419,5-hydroxy-1-methylimidazolidine-2,4-dione Preparation Products And Raw materials |
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