| Company Name: |
BOC Sciences |
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16314854226; +8616314854226 |
| Email: |
inquiry@bocsci.com |
Epitinib (succinate) manufacturers
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| | Epitinib (succinate) Basic information |
| | Epitinib (succinate) Chemical Properties |
| storage temp. | Store at -20°C | | form | Solid | | color | White to light yellow |
| | Epitinib (succinate) Usage And Synthesis |
| Uses | Epitinib succinate is an orally active and selective epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) designed for optimal brain penetration. Epitinib succinate can be used for the research of cancer[1][2]. Epitinib (succinate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | References | [1] Zhou et al. The safety profile of a selective EGFR TKI epitinib (HMPL-813) in patients with advanced solid tumors and preliminary clinical efficacy in EGFRm+ NSCLC patients with brain metastasis. Journal of Clinical Oncology 2016 34:15_suppl, e20502-e20502
[2] Zhou et al. Phase I study of the safety and pharmacokinetics of epitinib, an oral EGFR tyrosine kinase inhibitor, in patients with advanced solid tumors. Journal of Clinical Oncology 2013 31:15_suppl, e19042-e19042 |
| | Epitinib (succinate) Preparation Products And Raw materials |
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