L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]-

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L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]- Suppliers list
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L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]- manufacturers
L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]- Basic information
Product Name:L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]-
Synonyms:L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]-;Glucocorticoid receptor agonist-1 phosphate Gly-Glu-Br;(4S)-4-[2-(2-bromoacetamido)acetamido]-4-{[3-({4-[(1S,2S,4R,6R,8S,9S,11S,12S,13R)-11-hydroxy-9,13-dimethyl-16-oxo-8-[2-(phosphonooxy)acetyl]-5,7-dioxapentacyclo[10.8.0.02,?.0?,?.013,1?]icosa-14,17-dien-6-yl]phenyl}methyl)phenyl]carbamoyl}butanoic acid;(S)-4-(2-(2-Bromoacetamido)acetamido)-5-((3-(4-((6aR,6bS,7S,8aS,8bS,10R,11aR,12aS,12bS)-7-hydroxy-6a,8a-dimethyl-4-oxo-8b-(2-(phosphonooxy)acetyl)-2,4,6a,6b,7,8,8a,8b,11a,12,12a,12b-dodecahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-10-yl)benzyl)phenyl)amino)-5-oxopentanoic acid
CAS:2344809-82-9
MF:C44H51BrN3O14P
MW:956.77
EINECS:
Product Categories:ADC LINKER
Mol File:2344809-82-9.mol
L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]- Structure
L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]- Chemical Properties
density 1.56±0.1 g/cm3(Predicted)
pka1.66±0.10(Predicted)
form Solid
color White to light yellow
Safety Information
MSDS Information
L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]- Usage And Synthesis
UsesGlucocorticoid receptor agonist-1 phosphate Gly-Glu-Br is a drug-linker conjugate for ADC that can be used to synthesize ABBV-154, ABBV-927, ABBV-368 or their analogs[1].
References[1] Anti-cd40 antibody drug conjugates. WO 2019106608 A1.
L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]- Preparation Products And Raw materials
Tag:L-α-Glutamine, N-(2-bromoacetyl)glycyl-N-[3-[[4-[(R)-[[(11β,16α)-11-hydroxy-3,20-dioxo-21-(phosphonooxy)pregna-1,4-diene-16,17-diyl]bis(oxy)]methyl]phenyl]methyl]phenyl]-(2344809-82-9) Related Product Information
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