| Company Name: |
Nantong Hanfang Biotechnology Co. , Ltd.
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| Tel: |
hanfangpharma@126.com; 18616537568 |
| Email: |
hanfangpharma@126.com |
| Products Intro: |
Product Name:1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- CAS:2422030-94-0 Purity:98%+ Package:1g;5g;10g;100g; 1kg
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:BRM/BRG1 ATP Inhibitor-4 CAS:2422030-94-0 Package:100mg/RMB 19500;50mg/RMB 15300;25mg/RMB 11700
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1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- manufacturers
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| | 1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- Basic information |
| Product Name: | 1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- | | Synonyms: | 1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel-;BRM/BRG1 ATP Inhibitor-4 | | CAS: | 2422030-94-0 | | MF: | C25H32N6O3S | | MW: | 496.62 | | EINECS: | | | Product Categories: | | | Mol File: | 2422030-94-0.mol | ![1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- Structure](CAS/20210305/GIF/2422030-94-0.gif) |
| | 1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- Chemical Properties |
| density | 1.31±0.1 g/cm3(Predicted) | | pka | 7.95±0.50(Predicted) |
| | 1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- Usage And Synthesis |
| Uses | BRM/BRG1 ATP Inhibitor-4 is a BRG1/BRM inhibitor. BRM/BRG1 ATP Inhibitor-4 can be used for the research of cancers and BAF complex-related disorders[1]. | | in vivo | BRM/BRG1 ATP Inhibitor-4 (QD; 5, 15, 50 mg/kg) leds to tumor growth inhibition in a dose-dependent manner[1]. | Animal Model: | Nude mice[1] | | Dosage: | 5, 15, 50 mg/kg | | Administration: | QD | | Result: | Inhibited tumor growth and the size of tumors in mice engrafted with uveal melanoma cell lines. |
| | References | [1] Kevin J. Wilson, et al. Compounds and uses thereof. Patent. WO2021155320A1. |
| | 1H-Pyrrole-3-carboxamide, 1-(1,1-dimethylethyl)-N-[2-[[4-[6-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-2-pyridinyl]-2-thiazolyl]amino]-2-oxoethyl]-, rel- Preparation Products And Raw materials |
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