| Company Name: |
Chengdu Youngshe Chemical Co., Ltd.
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| Tel: |
+86-17380623303 +86-17380623303; |
| Email: |
Caroline@youngshechem.com |
| Products Intro: |
Product Name:A20FMDV2
CAS:932699-03-1
Purity:95% Package:1G; 10G; 100G
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| Company Name: |
Hangzhou Peptidego Biotech Co.,Ltd.
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| Tel: |
0571-87213919 |
| Email: |
Eric@peptidego.com |
| Products Intro: |
Product Name:A20FMDV2
CAS:932699-03-1
Purity:95% or 98% HPLC Package:1mg；5mg；10mg；50mg；100mg,1g or according to customer's detail requirement.
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| | A20FMDV2 Basic information |
| Product Name: | A20FMDV2 | | Synonyms: | L-Threonine, L-asparaginyl-L-alanyl-L-valyl-L-prolyl-L-asparaginyl-L-leucyl-L-arginylglycyl-L-α-aspartyl-L-leucyl-L-glutaminyl-L-valyl-L-leucyl-L-alanyl-L-glutaminyl-L-lysyl-L-valyl-L-alanyl-L-arginyl-;A20FMDV2 | | CAS: | 932699-03-1 | | MF: | C93H163N31O28 | | MW: | 2163.52 | | EINECS: | | | Product Categories: | | | Mol File: | 932699-03-1.mol |  |
| | A20FMDV2 Chemical Properties |
| density | 1.47±0.1 g/cm3(Predicted) | | form | Solid | | color | White to off-white | | Sequence | Asn-Ala-Val-Pro-Asn-Leu-Arg-Gly-Asp-Leu-Gln-Val-Leu-Ala-Gln-Lys-Val-Ala-Arg-Thr |
| | A20FMDV2 Usage And Synthesis |
| Uses | A20FMDV2 is a selective αvβ6 integrin inhibitor (IC50: 3 nM), with an activity 1,000-fold more selective for αvβ6 than for other RGD-directed integrins (αvβ3, αvβ5, and α5β1). A20FMDV2 can be derived from the foot-and-mouth disease virus. A20FMDV2 can be radiolabeled for the PET imaging of αvβ6 integrin-positive tumors[1]. | | References | [1] Hausner SH, et al. Use of a peptide derived from foot-and-mouth disease virus for the noninvasive imaging of human cancer: generation and evaluation of 4-[18F]fluorobenzoyl A20FMDV2 for in vivo imaging of integrin alphavbeta6 expression with positron emission tomography. Cancer Res. 2007 Aug 15;67(16):7833-40. DOI:10.1158/0008-5472.CAN-07-1026 |
| | A20FMDV2 Preparation Products And Raw materials |
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