- Ethyl Succinyl Chloride
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- $0.00 / 25KG
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2025-12-01
- CAS:14794-31-1
- Min. Order: 1KG
- Purity: 98.0%
- Supply Ability: 10000KGS
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| | Ethyl Succinyl Chloride Basic information |
| Product Name: | Ethyl Succinyl Chloride | | Synonyms: | BETA CARBETHOXY PROPIONYL CHLORIDE;ETHYL SUCCINYL CHLORIDE;ETHYL 4-CHLORO-4-OXOBUTYRATE;ETHYL 3-(CHLOROFORMYL)PROPIONATE;Ethyl siccinyl chloride;ETHYL 4-CHLORO-4-OXOBUTYRATE,95%;Ethyl succinyl chloride, tech., 95%;3-CARBETHOXYPROPIONYL CHLORIDE (Ethyl Succinyl Chloride) | | CAS: | 14794-31-1 | | MF: | C6H9ClO3 | | MW: | 164.59 | | EINECS: | 238-855-9 | | Product Categories: | bc0001 | | Mol File: | 14794-31-1.mol |  |
| | Ethyl Succinyl Chloride Chemical Properties |
| Hazard Codes | C | | Risk Statements | 34-36/37-14 | | Safety Statements | 26-27-36/37/39-45-24/25 | | RIDADR | UN 3265 8/PG 2 | | WGK Germany | 3 | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | II | | HS Code | 29171990 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Skin Corr. 1B |
| | Ethyl Succinyl Chloride Usage And Synthesis |
| Chemical Properties | clear colourless to yellow liquid | | Uses | Ethyl 4-chloro-4-oxobutyrate was used in the synthesis of:
- polymer-supported bifunctional catalyst
- succinimidyl ester of benzo(a)pyrene
- succinate prodrugs of curcuminoids
| | Flammability and Explosibility | Not classified | | Synthesis | The general procedure for the synthesis of monoethyl succinate chloride from monoethyl succinate: monoethyl succinate (116.8 g, 0.8 mol), dichloromethane (300 mL) and thionyl chloride (104 g, 0.88 mol) were added to a reaction flask, N,N-dimethylformamide (0.8 g) was added under nitrogen protection, and heated and stirred by refluxing for 5 hours at 38°C. The reaction was completed with a solution of dichloromethane (124 g, 0.88 mol). Upon completion of the reaction, a dichloromethane solution of monoethylsuccinic acid chloride (124 g, yield: 95%) was obtained. | | References | [1] Heterocycles, 2001, vol. 55, # 8, p. 1487 - 1498 [2] Journal of Medicinal Chemistry, 2007, vol. 50, # 7, p. 1528 - 1536 [3] Patent: CN104326922, 2016, B. Location in patent: Paragraph 0038; 0040 [4] Journal of the American Chemical Society, 1991, vol. 113, # 6, p. 2071 - 2092 [5] Journal of Organic Chemistry, 1996, vol. 61, # 14, p. 4848 - 4852 |
| | Ethyl Succinyl Chloride Preparation Products And Raw materials |
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