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Ethyl Succinyl Chloride

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Company Name: Hebei Chuanghai Biotechnology Co,.LTD
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Products Intro: Product Name:Ethyl Succinyl Chloride
CAS:14794-31-1
Purity:99% Package:1KG;5.00;USD|10KG;3.00;USD|50KG;2.00;USD
Company Name: Hebei Fengjia New Material Co., Ltd
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Products Intro: Product Name:Ethyl Succinyl Chloride
CAS:14794-31-1
Purity:0.99 Package:1kg;5USD
Company Name: Hebei Chuanghai Biotechnology Co., Ltd
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Products Intro: Product Name:Ethyl Succinyl Chloride
CAS:14794-31-1
Purity:99% Package:1KG;0.00;USD|250KG;0.00;USD|1000KG;0.00;USD
Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Ethyl 4-chloro-4-oxobutanoate
CAS:14794-31-1
Purity:98% Min. Package:1G;1KG;100KG
Company Name: Shanghai Bojing Chemical Co.,Ltd.
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Products Intro: Product Name:Hydroxylamine-O-sulfonic acid
CAS:14794-31-1
Purity:99% Package:1Kg;25kg;200Kg/ Drum or as customer request

Ethyl Succinyl Chloride manufacturers

Ethyl Succinyl Chloride Basic information
Product Name:Ethyl Succinyl Chloride
Synonyms:BETA CARBETHOXY PROPIONYL CHLORIDE;ETHYL SUCCINYL CHLORIDE;ETHYL 4-CHLORO-4-OXOBUTYRATE;ETHYL 3-(CHLOROFORMYL)PROPIONATE;Ethyl siccinyl chloride;ETHYL 4-CHLORO-4-OXOBUTYRATE,95%;Ethyl succinyl chloride, tech., 95%;3-CARBETHOXYPROPIONYL CHLORIDE (Ethyl Succinyl Chloride)
CAS:14794-31-1
MF:C6H9ClO3
MW:164.59
EINECS:238-855-9
Product Categories:bc0001
Mol File:14794-31-1.mol
Ethyl Succinyl Chloride Structure
Ethyl Succinyl Chloride Chemical Properties
Boiling point 88-90 °C11 mm Hg(lit.)
density 1.155 g/mL at 25 °C(lit.)
vapor pressure 48.2Pa at 25℃
refractive index n20/D 1.437(lit.)
Fp 184 °F
storage temp. 2-8°C
solubility soluble in Chloroform, Ethyl Acetate
form Liquid
color Clear colorless to yellow
Specific Gravity1.144 to 1.17
Water Solubility 59.01g/L at 25℃
Sensitive Moisture Sensitive
BRN 1766126
InChI1S/C6H9ClO3/c1-2-10-6(9)4-3-5(7)8/h2-4H2,1H3
InChIKeyIXZFDJXHLQQSGQ-UHFFFAOYSA-N
SMILESCCOC(=O)CCC(Cl)=O
LogP0.05
CAS DataBase Reference14794-31-1(CAS DataBase Reference)
NIST Chemistry ReferenceButanoic acid, 4-chloro-4-oxo-, ethyl ester(14794-31-1)
EPA Substance Registry SystemButanoic acid, 4-chloro-4-oxo-, ethyl ester (14794-31-1)
Safety Information
Hazard Codes C
Risk Statements 34-36/37-14
Safety Statements 26-27-36/37/39-45-24/25
RIDADR UN 3265 8/PG 2
WGK Germany 3
TSCA TSCA listed
HazardClass 8
PackingGroup II
HS Code 29171990
Storage Class8A - Combustible corrosive hazardous materials
Hazard ClassificationsSkin Corr. 1B
MSDS Information
ProviderLanguage
Ethyl 3-(chloroformyl)propionate English
SigmaAldrich English
ACROS English
ALFA English
Ethyl Succinyl Chloride Usage And Synthesis
Chemical Propertiesclear colourless to yellow liquid
UsesEthyl 4-chloro-4-oxobutyrate was used in the synthesis of:
  • polymer-supported bifunctional catalyst
  • succinimidyl ester of benzo(a)pyrene
  • succinate prodrugs of curcuminoids
Flammability and ExplosibilityNot classified
Synthesis
MONO-ETHYL SUCCINATE

1070-34-4

Ethyl Succinyl Chloride

14794-31-1

The general procedure for the synthesis of monoethyl succinate chloride from monoethyl succinate: monoethyl succinate (116.8 g, 0.8 mol), dichloromethane (300 mL) and thionyl chloride (104 g, 0.88 mol) were added to a reaction flask, N,N-dimethylformamide (0.8 g) was added under nitrogen protection, and heated and stirred by refluxing for 5 hours at 38°C. The reaction was completed with a solution of dichloromethane (124 g, 0.88 mol). Upon completion of the reaction, a dichloromethane solution of monoethylsuccinic acid chloride (124 g, yield: 95%) was obtained.

References[1] Heterocycles, 2001, vol. 55, # 8, p. 1487 - 1498
[2] Journal of Medicinal Chemistry, 2007, vol. 50, # 7, p. 1528 - 1536
[3] Patent: CN104326922, 2016, B. Location in patent: Paragraph 0038; 0040
[4] Journal of the American Chemical Society, 1991, vol. 113, # 6, p. 2071 - 2092
[5] Journal of Organic Chemistry, 1996, vol. 61, # 14, p. 4848 - 4852
Tag:Ethyl Succinyl Chloride(14794-31-1) Related Product Information
Butyryl chloride Diisopropyl succinate 4-CHLOROBUTYRIC ACID Sodium propionate SUCCINALDEHYDIC ACID SUCCINALDEHYDE Methyl 4-chlorobutyrate 1-Chlorobutane Methyl 4-chloro-4-oxobutanoate Methyl 4-oxobutanoate Methyl butyrate Butyl ethyl ether Ethyl Succinyl Chloride 1-Propanol ETHYL 4-CHLOROBUTYRATE 1-Butanol Butyric Acid 4-Chlorobutyl methyl ether