| Company Name: |
Suzhou Zhixin Biotechnology Co., Ltd.
|
| Tel: |
0512-65118909 15162312715 |
| Email: |
sales@szzxbio.com |
| Products Intro: |
Product Name:AMC-01
CAS:1047978-71-1
Purity:98%+ Package:1g;10g;100g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:AMC-01
CAS:1047978-71-1
Purity:97% Package:1mg;5mg;10mg
|
Methanone, [1,1'-biphenyl]-4-yl[4-[(5-bromo-2-methoxyphenyl)methyl]-1-piperazinyl]-, ethanedioate (1:1) manufacturers
- AMC-01
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- $350.00 / 1mg
-
2024-11-19
- CAS:1047978-71-1
- Min. Order:
- Purity: 97.49%
- Supply Ability: 10g
|
| | Methanone, [1,1'-biphenyl]-4-yl[4-[(5-bromo-2-methoxyphenyl)methyl]-1-piperazinyl]-, ethanedioate (1:1) Basic information |
| | Methanone, [1,1'-biphenyl]-4-yl[4-[(5-bromo-2-methoxyphenyl)methyl]-1-piperazinyl]-, ethanedioate (1:1) Chemical Properties |
| form | Solid | | color | White to off-white |
| | Methanone, [1,1'-biphenyl]-4-yl[4-[(5-bromo-2-methoxyphenyl)methyl]-1-piperazinyl]-, ethanedioate (1:1) Usage And Synthesis |
| Description | AMC-01 induces the inactivation of eIF2-alpha by phosphorylation of serine residue 51 in a dose- and time-dependent manner. | | Uses | AMC-01 is a potent chemical probe that regulates eIF2-α activity. AMC-01 induces protein kinase RNA activation (PKR) kinase and nuclear factor κb (NF-κB). AMC-01 inhibits apoptosis[1]. | | References | [1] Hong MN, et al. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016 May;21(3):485-97. DOI:10.1007/s12192-016-0677-5 |
| | Methanone, [1,1'-biphenyl]-4-yl[4-[(5-bromo-2-methoxyphenyl)methyl]-1-piperazinyl]-, ethanedioate (1:1) Preparation Products And Raw materials |
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