A23187 (MIXED CALCIUM-MAGNESIUM SALT)

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A23187 (MIXED CALCIUM-MAGNESIUM SALT) Basic information
Product Name:A23187 (MIXED CALCIUM-MAGNESIUM SALT)
Synonyms:A23187 (MIXED CALCIUM-MAGNESIUM SALT);A23187;A23187-MG/CA;A23187 (MG/CA SALT);A23187 CA-MG SALT;CALCIUM IONOPHORE A23187 MIXED CALCIUM-MAGNESIUM SALT;CALCIMYCIN MIXED CALCIUM MAGNESIUM SALT;(CALEIMYCIN) MIXED CALCIUM-MAGNESIUM SALT
CAS:
MF:C112H132CaMgN8O24
MW:2038.67
EINECS:
Product Categories:antibiotic
Mol File:Mol File
A23187 (MIXED CALCIUM-MAGNESIUM SALT) Structure
A23187 (MIXED CALCIUM-MAGNESIUM SALT) Chemical Properties
Melting point 307-311 °C
storage temp. 2-8°C
solubility DMSO: soluble
ethanol: soluble
form crystalline solid
color yellow
Major Applicationdiagnostic assay manufacturing
hematology
histology
InChIKeyHKVXGTQLKZNXPV-UHFFFAOYSA-N
SMILES[Mg++].[Ca++].CNc1ccc2oc(CC3OC4(CCC3C)OC(C(C)CC4C)C(C)C(=O)c5ccc[nH]5)nc2c1C(O)=O
Safety Information
Hazard Codes Xn
Risk Statements 20/21/22-36/37/38
Safety Statements 26-36/37
WGK Germany 3
HS Code 2941900000
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
A23187 (MIXED CALCIUM-MAGNESIUM SALT) Usage And Synthesis
UsesCalcium Ionophore A23187 mixed calcium magnesium salt has been used as a calcium ionophore to increase the intracellular levels of calcium.
Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not to quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.
Biological ActivityCell permeable: no', 'Primary Target
Useful in cell activation experiments when calcium dose-response data are not required', 'Product does not compete with ATP.', 'Reversible: no
A23187 (MIXED CALCIUM-MAGNESIUM SALT) Preparation Products And Raw materials
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