甲硫米特
| 中文名称 | 甲硫米特 |
|---|---|
| 中文同义词 | 甲硫米特;1-甲基-3-(2-(((5-甲基-1H-咪唑-4-基)甲基)硫基)乙基)硫脲;甲硫米特,10 MM DMSO 溶液 |
| 英文名称 | Metiamide |
| 英文同义词 | Metiamide;1-Methyl-3-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]thiourea;N-Methyl-N'-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]thiourea;SKF-92058;1-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]thiourea;CS-159;MetiaMide hydrochloride;MetiaMide HCl |
| CAS号 | 34839-70-8 |
| 分子式 | C9H16N4S2 |
| 分子量 | 244.38 |
| EINECS号 | 200-258-5 |
| 相关类别 | 抑制剂 |
| Mol文件 | 34839-70-8.mol |
| 结构式 |  |
甲硫米特 性质
| 沸点 | 463.0±55.0 °C(Predicted) |
|---|---|
| 密度 | 1.245±0.06 g/cm3(Predicted) |
| 储存条件 | Sealed in dry,Store in freezer, under -20°C |
| 溶解度 | 溶于水 |
| 形态 | 固体 |
| 酸度系数(pKa) | 14.14±0.10(Predicted) |
| 颜色 | 白色至米白色 |
| InChI | InChI=1S/C9H16N4S2/c1-7-8(13-6-12-7)5-15-4-3-11-9(14)10-2/h6H,3-5H2,1-2H3,(H,12,13)(H2,10,11,14) |
| InChIKey | FPBPLBWLMYGIQR-UHFFFAOYSA-N |
| SMILES | N(C)C(NCCSCC1NC=NC=1C)=S |
Metiamide (SK&F 92058) 是组胺H2受体拮抗剂。
Ki: 0.92 uM (H2 receptor)
Metiamide (SK&F 92058) is a competitive with aldehyde substrates and noncompetitive with the Human E3 Aldehyde Dehydrogenase coenzyme, binding to both the free E3 isozyme and the enzyme·coenzyme binary complex with K i values of 0.92 μM glycolaldehyde as the varied substrate. Data is got as percentage change in GTPase activity induced by metiamide compared with the GTPase activity stimulated by HA (100 μM).
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2025/12/22 | HY-15540 | 甲硫米特 Metiamide | 34839-70-8 | 1 mg | 706元 |
| 2025/12/22 | HY-15540 | 甲硫米特 Metiamide | 34839-70-8 | 2mg | 1000元 |