| Company Name: |
TargetMol Chemicals Inc.
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15002134094 |
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marketing@targetmol.cn |
| Products Intro: |
Product Name:SARS-CoV-2 nsp13-IN-5 CAS:912799-11-2 Package:25mg/RMB 10600;100mg/RMB 17500;50mg/RMB 13800
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Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- manufacturers
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| | Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- Basic information |
| Product Name: | Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- | | Synonyms: | Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo-;SARS-CoV-2 nsp13-IN-5 | | CAS: | 912799-11-2 | | MF: | C28H30N4O4S | | MW: | 518.63 | | EINECS: | | | Product Categories: | | | Mol File: | 912799-11-2.mol | ![Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- Structure](CAS/20210305/GIF/912799-11-2.gif) |
| | Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- Chemical Properties |
| density | 1.290±0.06 g/cm3(Predicted) | | pka | 13.80±0.70(Predicted) |
| | Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- Usage And Synthesis |
| Uses | SARS-CoV-2 nsp13-IN-5 (compound C6) is a potent SARS-CoV-2 nsp13 inhibitor with IC50 values of 50 and 55 μM for ssDNA+ ATPase and ssDNA- ATPase. SARS-CoV-2 nsp13-IN-5 can be used for researching anti-COVID-19[1]. | | References | [1] Yazdi AK, et al. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors. ACS Infect Dis. 2022 Jul 13. DOI:10.1021/acsinfecdis.2c00165 |
| | Thieno[3,2-d]pyrimidine-3(2H,4H)-butanamide, 1-[2-[(2,6-dimethylphenyl)amino]-2-oxoethyl]-N-[(4-methylphenyl)methyl]-2,4-dioxo- Preparation Products And Raw materials |
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