| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:NF-κB/PON1-IN-1
CAS:2419107-97-2
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
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Acetamide, 2-[[3-[4-(aminosulfonyl)phenyl]-3,4-dihydro-4-oxo-2-quinazolinyl]thio]-N-2-pyrazinyl- manufacturers
- NF-κB/PON1-IN-1
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- $1520.00 / 25mg
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2025-05-02
- CAS:2419107-97-2
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Acetamide, 2-[[3-[4-(aminosulfonyl)phenyl]-3,4-dihydro-4-oxo-2-quinazolinyl]thio]-N-2-pyrazinyl- Basic information |
| | Acetamide, 2-[[3-[4-(aminosulfonyl)phenyl]-3,4-dihydro-4-oxo-2-quinazolinyl]thio]-N-2-pyrazinyl- Chemical Properties |
| density | 1.58±0.1 g/cm3(Predicted) | | pka | 10.12±0.10(Predicted) |
| | Acetamide, 2-[[3-[4-(aminosulfonyl)phenyl]-3,4-dihydro-4-oxo-2-quinazolinyl]thio]-N-2-pyrazinyl- Usage And Synthesis |
| Uses | NF-κB/PON1-IN-1 (Compound 16) is a NF-κB/PON1 pathway inhibitor. NF-κB/PON1-IN-1 has antioxidant (IC50 = 45.76 μM) and hepatoprotective activities[1]. | | References | [1] Soliman AM, et al. Antioxidant activity of novel quinazolinones bearing sulfonamide: Potential radiomodulatory effects on liver tissues via NF-κB/ PON1 pathway. Eur J Med Chem. 2020 Jul 1;197:112333. DOI:10.1016/j.ejmech.2020.112333 |
| | Acetamide, 2-[[3-[4-(aminosulfonyl)phenyl]-3,4-dihydro-4-oxo-2-quinazolinyl]thio]-N-2-pyrazinyl- Preparation Products And Raw materials |
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