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| Product Name: | Cytidine 5'-triphosphate disodium salt | | Synonyms: | CYTIDINE-5'-TRIPHOSPHATE DISODIUM SALT 98%;CYTIDINE-5'-TRIPHOSPHATE DISODIUM SALT;CYTIDINE-5'-TRIPHOSPHORIC ACID, DISODIUM;CTP DISODIUM SALT;CTP, NA2H2;disodium [[[5-(6-amino-2-oxo-1H-pyrimidin-3-ium-3-yl)-3,4-dihydroxy-2-oxolanyl]methoxy-hydroxyphosphoryl]oxy-oxidophosphoryl] hydrogen phosphate;Cytidine5'-(tetrahydrogen triphos;cytidine5’-(disodiumdihydrogentriphosphate) | | CAS: | 36051-68-0 | | MF: | C9H17N3NaO14P3 | | MW: | 507.15 | | EINECS: | 252-849-3 | | Product Categories: | Material;Pharmaceutical;nucleoside | | Mol File: | 36051-68-0.mol |  |
| | Cytidine 5'-triphosphate disodium salt Chemical Properties |
| Fp | 113 °C | | storage temp. | -20°C | | solubility | H2O: 50 mg/mL, clear, colorless | | form | Powder | | color | White | | Water Solubility | Soluble in water. Insoluble in ethanol, chloroform and ether. | | InChIKey | LGADHEWLYMMGHW-RFFBCSJBNA-N | | SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.[NaH] |&1:1,2,3,19,r| | | CAS DataBase Reference | 36051-68-0(CAS DataBase Reference) |
| Safety Statements | 24/25 | | WGK Germany | 3 | | F | 10-21 | | HS Code | 29349990 | | Storage Class | 11 - Combustible Solids |
| | Cytidine 5'-triphosphate disodium salt Usage And Synthesis |
| Description | Cytidine 5'-triphosphate disodium salt is a nucleoside triphosphate with a pyrimidine ring, which is present in RNA. It is a nucleotide derivative and is involved in phospholipid anabolism in vivo. It can cross the blood-cerebrospinal fluid barrier. It is the intermediate product and energy source of cephalin synthesis and nucleic acid metabolism. It can also improve the stability and reconstruction ability of nerve cell membrane structure, support nerve cell survival, delay cell aging and death, and improve nerve cells. Injury resistance, promote neurite outgrowth. | | Pharmacological action | Disodium cytidine triphosphate is a nucleotide derivative. It participates in phospholipid synthesis and metabolism in the body and can pass through the blood-cerebrospinal fluid barrier. It is an intermediate product and energy source between cephalin synthesis and nucleic acid metabolism, and promotes the repair of liver cells after injury , for the myocardial and brain tissue caused by vascular sclerosis, nutrition, promote regeneration and repair. | | Chemical Properties | White powder | | Uses | Cytidine 5'-triphosphate disodium salt is a pyrimidine nucleoside triphosphate salt that is involved in a variety of biochemical reactions. It is used in the synthesis of RNA by RNA polymerases. In the formation of phosphatidylcholine (PC), CTP reacts with phosphocholine, via CTP:phosphocholine cytidylyltransferases, to produce CDP-choline and diphosphate. This is the rate-limiting step in PC synthesis and, as a pivotal step in cell proliferation, can be important in cancer. CTP also interacts with N-acylneuraminate, in a reaction mediated by N-acylneuraminate cytidylyltransferase, to generate an intermediate that is required for sialylation, namely CMP-N-acylneuraminic acid.[Cayman Chemical] | | Uses | Cytidine-5'-triphosphate disodium salt is a cation-permeable ligand gated ion channel (P2X purinergic receptor) agonist. It is also used as an organic intermediate, pharmaceutical intermediate, food additive and flavoring agent. | | Application | Cytidine 5'-triphosphate disodium salt can be used as a phosphate source for the synthesis of amorphous calcium phosphate (ACP) nanoparticles and hydroxyapatite (HAP) microspheres. | | General Description | Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA. | | Biochem/physiol Actions | Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation. | | Clinical Use | Cytidine Disodium Triphosphate (CTP-2Na) for injection is mainly used for treating nervous system diseases. | | IC 50 | Human Endogenous Metabolite |
| | Cytidine 5'-triphosphate disodium salt Preparation Products And Raw materials |
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