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2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- Suppliers list
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| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Nrf2 activator-5
CAS:1012860-13-7
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- manufacturers
- Nrf2 activator-5
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- $1980.00 / 50mg
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2026-01-05
- CAS:1012860-13-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- Basic information |
| Product Name: | 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- | | Synonyms: | 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)-;Nrf2 activator-5 | | CAS: | 1012860-13-7 | | MF: | C25H30Cl2O6 | | MW: | 497.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1012860-13-7.mol | ![2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- Structure](CAS/20210305/GIF/1012860-13-7.gif) |
| | 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- Chemical Properties |
| Boiling point | 688.8±55.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | pka | 6.14±0.70(Predicted) |
| | 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- Usage And Synthesis |
| Uses | Nrf2 activator-5 (compound 1) is a potent Nrf2 activator that can attenuate H2O2-induced oxidative stress and LPS-stimulated inflammation in BV-2 microglial cells. Nrf2 activator-5 exhibits antioxidant and anti-inflammatory activities[1]. | | References | [1] Choi JW, et, al. Identification and evaluation of a napyradiomycin as a potent Nrf2 activator: Anti-oxidative and anti-inflammatory activities. Bioorg Chem. 2020 Dec;105:104434. DOI:10.1016/j.bioorg.2020.104434 |
| | 2H-Naphtho[2,3-b]pyran-5,10-dione, 3,4a-dichloro-3,4,4a,10a-tetrahydro-6,8-dihydroxy-10a-[(2E,6E)-8-hydroxy-3,7-dimethyl-2,6-octadien-1-yl]-2,2-dimethyl-, (3R,4aR,10aS)- Preparation Products And Raw materials |
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