2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1)

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2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1) Suppliers list
Company Name: Daicel Chiral Technologies (China)CO.,LTD  
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Company Name: Shanghai Haohong Scientific Co., Ltd.  
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2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1) Basic information
Product Name:2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1)
Synonyms:2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1);3-((3-Fluoro-4-(piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride
CAS:2654822-04-3
MF:C16H21ClFN3O2
MW:341.81
EINECS:
Product Categories:
Mol File:2654822-04-3.mol
2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1) Structure
2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1) Chemical Properties
storage temp. 2-8°C
form powder or crystals
color off-white to beige
InChI1S/C16H20FN3O2.ClH/c17-13-9-11(19-14-3-4-15(21)20-16(14)22)1-2-12(13)10-5-7-18-8-6-10;/h1-2,9-10,14,18-19H,3-8H2,(H,20,21,22);1H
InChIKeyVJQKECGXGMCYHY-UHFFFAOYSA-N
SMILESCl.O=C1NC(=O)C(NC2=CC=C(C(F)=C2)C3CCNCC3)CC1
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1) Usage And Synthesis
UsesA functionalized cereblon ligand for development of Thalidomide based PROTACs. Allows rapid conjugation with carboxyl linkers due to presence of amine group via peptide coupling reactions. Amenable for linker attachment via reductive amination, and a basic building block for making protein degrader library.
Technology Spotlight:
targeted protein degradation
When used with other protein degrader building blocks
Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1) Preparation Products And Raw materials
Tag:2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]-, hydrochloride (1:1)(2654822-04-3) Related Product Information
3-((4-(piperidin-4-yl)phenyl)amino)piperidine-2,6-dione dihydrochloride 3-((4-(Piperidin-4-yl)phenyl)amino)piperidine-2,6-dione hydrochloride 2,6-Piperidinedione, 3-[[3-fluoro-4-(4-piperidinyl)phenyl]amino]- 2,6-Piperidinedione, 3-[[4-(4-piperidinyl)phenyl]amino]-