3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)-

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3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- Basic information
Product Name:3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)-
Synonyms:3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)-;6-(4-phenylpiperazin-1-yl)pyridine-3-carboxamidine
CAS:1016866-61-7
MF:C16H19N5
MW:281.36
EINECS:
Product Categories:
Mol File:1016866-61-7.mol
3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- Structure
3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- Chemical Properties
Boiling point 497.4±55.0 °C(Predicted)
density 1.25±0.1 g/cm3(Predicted)
pka12.32±0.50(Predicted)
Safety Information
MSDS Information
3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- Usage And Synthesis
UsesC1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a Kd of 9.8 μM[1].
References[1] Xu X, et al. Inhibition of the C1s Protease and the Classical Complement Pathway by 6-(4-Phenylpiperazin-1-yl)Pyridine-3-Carboximidamide and Chemical Analogs. J Immunol. 2024 Feb 15;212(4):689-701. DOI:10.4049/jimmunol.2300630
3-Pyridinecarboximidamide, 6-(4-phenyl-1-piperazinyl)- Preparation Products And Raw materials
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