Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]-

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Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]- Suppliers list
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]- manufacturers

  • MMP-2/9-IN-1
  • MMP-2/9-IN-1 pictures
  • $2785.00
  • 2026-07-27
  • CAS:2415311-84-9
  • Purity:
  • Supply Ability: 10g
Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]- Basic information
Product Name:Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]-
Synonyms:Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]-;MMP-2/9-IN-1
CAS:2415311-84-9
MF:C14H16IN7S
MW:441.29
EINECS:
Product Categories:
Mol File:2415311-84-9.mol
Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]- Structure
Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]- Chemical Properties
Boiling point 549.8±60.0 °C(Predicted)
density 1.77±0.1 g/cm3(Predicted)
pka11.21±0.10(Predicted)
Safety Information
MSDS Information
Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]- Usage And Synthesis
UsesMMP-2/9-IN-1 (Compound 4a) is a potent dual MMP-2 and MMP-9 inhibitor with IC50 values of 56 nM and 38 nM, respectively. MMP-2/9-IN-1 inhibits tumor growth, strongly induces cancer cell apoptosis, inhibits cell migration, and suppresses cell cycle progression leading to DNA fragmentation[1].
IC 50MMP-9: 38 nM (IC50); MMP-2: 56 nM (IC50)
References[1] Omar AM, et al. Novel molecular discovery of promising amidine-based thiazole analogues as potent dual Matrix Metalloproteinase-2 and 9 inhibitors: Anticancer activity data with prominent cell cycle arrest and DNA fragmentation analysis effects. Bioorg Ch DOI:10.1016/j.bioorg.2020.103992
Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]- Preparation Products And Raw materials
Tag:Hydrazinecarboximidamide, 2-[1-[2-[(2E)-2-[(4-iodophenyl)methylene]hydrazinyl]-4-methyl-5-thiazolyl]ethylidene]-(2415311-84-9) Related Product Information
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