Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-

Request For Quotation
Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]- Basic information
Product Name:Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-
Synonyms:Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-;HER2-IN-6
CAS:2691891-38-8
MF:C26H32N8O3
MW:504.58
EINECS:
Product Categories:
Mol File:2691891-38-8.mol
Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]- Structure
Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]- Chemical Properties
density 1.35±0.1 g/cm3(Predicted)
pka10.24±0.70(Predicted)
Safety Information
MSDS Information
Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]- Usage And Synthesis
UsesHER2-IN-6 is a potent inhibitor of HER2. HER2-IN-6 has the potential for the research of wild and/or mutant EGFR and/or HER2 kinase mediated tumor (extracted from patent WO2021164697A1, compound 11)[1].
References[1] Yihan Wang, et al. Substituted amide derivative and composition thereof and use thereof. Patent WO2021164697A1.
Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]- Preparation Products And Raw materials
Tag:Imidazo[5,1-f][1,2,4]triazine-5-carboxamide, 4-amino-N-[4-[2-(dimethylamino)-2-oxoethyl]-2,3-dimethylphenyl]-7-[(3R)-1-(1-oxo-2-propen-1-yl)-3-piperidinyl]-(2691891-38-8) Related Product Information
EGFR Protein, HUMAN (621A.A, HEK293, FC) EGFR protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) HER2/CD340 protein, HUMAN (BIOTINYLATED, HEK293, HIS) HER3 Protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) Zanidatamab Amivantamab