Benzonitrile, 4-[1-hydroxy-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-propen-1-yl]- manufacturers
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| | Benzonitrile, 4-[1-hydroxy-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-propen-1-yl]- Basic information |
| | Benzonitrile, 4-[1-hydroxy-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-propen-1-yl]- Chemical Properties |
| Boiling point | 577.4±60.0 °C(Predicted) | | density | 1.32±0.1 g/cm3(Predicted) | | pka | 11.78±0.20(Predicted) |
| | Benzonitrile, 4-[1-hydroxy-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-propen-1-yl]- Usage And Synthesis |
| Uses | Antiparasitic agent-6 (compound 5b) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 3.89 μM. Antiparasitic agent-6 also has certain cytotoxicity against HepG2 (CC50 = 13.64 μM)[1]. | | References | [1] Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418. DOI:10.1016/j.ejmech.2020.112418 |
| | Benzonitrile, 4-[1-hydroxy-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-propen-1-yl]- Preparation Products And Raw materials |
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