Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)-

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Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)- Suppliers list
Company Name: TargetMol Chemicals Inc.
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Products Intro: Product Name:(S)-Terazosin
CAS:109351-33-9
Purity:98.00% Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；200 mg；5 mg；50 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: BOC Sciences
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Products Intro: Product Name:(S)-Terazosin
CAS:109351-33-9
Purity:99% Remarks:Please reach out to us for more information about custom solutions.
Company Name: InvivoChem
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Products Intro: Product Name:(S)-Terazosin
CAS:109351-33-9
Purity:98% Package:5mg Remarks:V37874
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
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Products Intro: Product Name:(S)-Terazosin
CAS:109351-33-9
Package:2mg;119USD|5mg;198USD|50mg;789USD
Company Name: ShangHai Caerulum Pharma Discovery Co., Ltd.  
Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Products Intro: Product Name:(S)-Terazosin
CAS:109351-33-9
Purity:98% Package:1g;10g;100g

Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)- manufacturers

  • (S)-Terazosin
  • (S)-Terazosin pictures
  • $98.00
  • 2026-07-22
  • CAS:109351-33-9
  • Purity:
  • Supply Ability: 10g
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)- Basic information
Product Name:Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)-
Synonyms:Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)-;Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[[(2S)-tetrahydro-2-furanyl]carbonyl]- (9CI);(S)-Terazosin;(S) Terazosin,(S)Terazosin;Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(2S)-tetrahydro-2-furanyl]-;(S)-(4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
CAS:109351-33-9
MF:C19H25N5O4
MW:387.43
EINECS:
Product Categories:
Mol File:109351-33-9.mol
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)- Structure
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)- Chemical Properties
Boiling point 664.5±65.0 °C(Predicted)
density 1.332±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO: 150 mg/mL (387.17 mM)
pka6.52±0.50(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)- Usage And Synthesis
Uses(S)-Terazosin is an active S-enantiomer of Terazosin. (S)-Terazosin is a potent and high-affinity α-adrenoceptor antagonist with Ki values of 3.91 nM, 0.79 nM and 1.16 nM for α1a, α1b and α1d-adrenoceptor, respectively. (S)-Terazosin also has high-affinity for α2a, α2B and α2c-adrenoceptor with Ki values of 729 nM, 3.5 nM and 46.4 nM, respectively[1].
in vivo

(S)-Terazosin shows antagonism of at rat atrial α2B receptor with a pEC30 of 6.93. (s)-Terazosin shows antagonism of at rat vas deferens α1A and α2A receptor with pA2 values of 8.3 and 6.12, respectively[1].

IC 50α adrenergic receptor
References[1] Hancock AA, et al. Actions of terazosin and its enantiomers at subtypes of alpha 1- and alpha 2-adrenoceptors in vitro. J Recept Signal Transduct Res. 1995 Sep-Dec;15(7-8):863-85. DOI:10.3109/10799899509049862
Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (S)- Preparation Products And Raw materials
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