| Company Name: |
Tianjin Kailiqi Biotechnology Co., Ltd.
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| Tel: |
15076683720 |
| Email: |
klq@cw-bio.com |
| Products Intro: |
Product Name:VEGFR-2-IN-22 CAS:2447587-73-5 Purity:大于98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
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| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:VEGFR-2-IN-22 CAS:2447587-73-5 Package:50mg/RMB 13800;100mg/RMB 17500;25mg/RMB 10600
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1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- manufacturers
- VEGFR-2-IN-22
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- $1980.00
-
2026-07-27
- CAS:2447587-73-5
- Purity:
- Supply Ability: 10g
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| | 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- Basic information |
| Product Name: | 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- | | Synonyms: | 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-;VEGFR-2-IN-22 | | CAS: | 2447587-73-5 | | MF: | C26H24ClFN4O6 | | MW: | 542.94 | | EINECS: | | | Product Categories: | | | Mol File: | 2447587-73-5.mol |  |
| | 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- Chemical Properties |
| density | 1.36±0.1 g/cm3(Predicted) | | pka | 9.65±0.70(Predicted) |
| | 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- Usage And Synthesis |
| Uses | VEGFR-2-IN-22 (Compound 25) is a dual VEGFR-2 and β-tubulin polymerization inhibitor with an IC50 of 19.82 nM against VEGFR-2. VEGFR-2-IN-22 induces apoptosis[1]. | | IC 50 | VEGFR2: 19.82 nM (IC50) | | References | [1] Abdelhameid MK, et al. Design, synthesis, and cytotoxic screening of novel azole derivatives on hepatocellular carcinoma (HepG2 Cells). Bioorg Chem. 2020 Aug;101:103995. DOI:10.1016/j.bioorg.2020.103995 |
| | 1H-1,2,4-Triazole-3-carboxamide, 1-(3-chloro-4-fluorophenyl)-N-(3,4-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)- Preparation Products And Raw materials |
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