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| | (S)-(-)-2-Azetidinecarboxylic acid Basic information |
| | (S)-(-)-2-Azetidinecarboxylic acid Chemical Properties |
| Melting point | ~215 °C (dec.) | | alpha | -125 º (c=1, water 25 ºC) | | Boiling point | 189.47°C (rough estimate) | | density | 1.2245 (rough estimate) | | refractive index | -122 ° (C=4, H2O) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Aqueous Base (Slightly), Methanol (Slightly), Water (Slightly) | | pka | 2.35±0.20(Predicted) | | form | Crystalline Powder or Crystals | | color | White to light beige | | Water Solubility | 5 g/100 mL | | Merck | 14,908 | | BRN | 80678 | | InChIKey | IADUEWIQBXOCDZ-VKHMYHEASA-N | | CAS DataBase Reference | 2133-34-8(CAS DataBase Reference) |
| | (S)-(-)-2-Azetidinecarboxylic acid Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | Specific proline antagonist. Used in synthesis of abnormally high molecular weight polypeptides. | | Uses | (S)-(-)-2-Azetidinecarboxylic acid is a four-membered ring analog of L-Proline, It is a useful intermediate in the synthesis of polypeptides,Used in synthesis of abnormally high molecular weight polypeptides. | | Uses | L-Azetidine-2-carboxylic acid has been used as a:
- collagen synthesis inhibitor
- protein folding antagonist
- as a standard in liquid chromatography-mass spectrometry
| | Definition | ChEBI: The (S)-enantiomer of azetidine-2-carboxylic acid. | | General Description | L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature. | | Biochem/physiol Actions | Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding. | | Safety Profile | Moderately toxic by subcutaneousroute. An experimental teratogen. Other experimentalreproductive effects. When heated to decomposition itemits toxic fumes of NOx. |
| | (S)-(-)-2-Azetidinecarboxylic acid Preparation Products And Raw materials |
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