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Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)-

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Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)- Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:JTP-117968
CAS:2250132-99-9
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)- Basic information
Product Name:Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)-
Synonyms:Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)-
CAS:2250132-99-9
MF:C31H31F3N2O2
MW:520.6
EINECS:
Product Categories:
Mol File:2250132-99-9.mol
Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)- Structure
Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)- Chemical Properties
Boiling point 579.6±50.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
pka12.30±0.40(Predicted)
Safety Information
MSDS Information
Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)- Usage And Synthesis
UsesJTP-117968, a novel selective glucocorticoid receptor modulator (a non-steroidal SGRM, IC50 of 6.8 nM), exhibits improved transrepression/transactivation dissociation[1].
References[1] Takafumi Kurimoto, et al. JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits improved transrepression/transactivation dissociation. Eur J Pharmacol. 2017 May 15;803:179-186. DOI:10.1016/j.ejphar.2017.03.057
Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)- Preparation Products And Raw materials
Tag:Spiro[cyclopropane-1,9'(5'H)-phenanthrene]-2'-carboxamide, 4'b,6',7',8',8'a,10'-hexahydro-7'-hydroxy-N-(2-methyl-3-pyridinyl)-4'b-(phenylmethyl)-7'-(trifluoromethyl)-, (4'bS,7'R,8'aS)-(2250132-99-9) Related Product Information
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