- kauran-16,17-diol
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- $62.00 / 1mg
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2026-05-11
- CAS:16836-31-0
- Min. Order:
- Purity: 99.93%
- Supply Ability: 10g
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| | kauran-16,17-diol Basic information |
| Product Name: | kauran-16,17-diol | | Synonyms: | kauran-16,17-diol;ent-kauran-16β,17-diol;ent-kauran;ent-Kaurane-16β,17-diol;(4aR,6aS,8R,9S,11aR,11bR)-8-(Hydroxymethyl)-4,4,11b-trimethyltetradecahydro-6a,9-methanocyclohepta[a]naphthalen-8-ol;Kauran-16,17-diol (ent-Kauran-16beta,17-diol);inhibit,Inhibitor,Apoptosis,kauran16,17diol,kauran 16,17 diol;kauran-16,17-diol, 10 mM in DMSO | | CAS: | 16836-31-0 | | MF: | C20H34O2 | | MW: | 306.48 | | EINECS: | | | Product Categories: | | | Mol File: | 16836-31-0.mol |  |
| | kauran-16,17-diol Chemical Properties |
| Melting point | 193-194 °C | | Boiling point | 422.3±18.0 °C(Predicted) | | density | 1.09±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 14.48±0.60(Predicted) | | form | Solid | | color | White to off-white |
| | kauran-16,17-diol Usage And Synthesis |
| Uses | Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2]. | | References | [1] Alvaro Morales, et al. The natural diterpene ent-16β-17α-dihydroxykaurane down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells. Apoptosis. 2011 Dec;16(12):1245-52. DOI:10.1007/s10495-011-0638-5
[2] Nguyen Xuan Nhiem, et al. New ent-kauranes from the fruits of Annona glabra and their inhibitory nitric oxide production in LPS-stimulated RAW264.7 macrophages. Bioorg Med Chem Lett. 2015 Jan 15;25(2):254-8. DOI:10.1016/j.bmcl.2014.11.059 |
| | kauran-16,17-diol Preparation Products And Raw materials |
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