| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
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marketing@targetmol.cn |
| Products Intro: |
Product Name:PD 114595
CAS:94636-28-9
Package:25mg/RMB 13900;50mg/RMB 18300;100mg/RMB 23500
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PD 114595 manufacturers
- PD 114595
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- $1970.00 / 25mg
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2025-08-21
- CAS:94636-28-9
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | PD 114595 Basic information |
| Product Name: | PD 114595 | | Synonyms: | PD 114595;2-[2-(Diethylamino)ethyl]-5-[[2-[(2-hydroxyethyl)amino]ethyl]amino]-2H-[1]benzothiopyrano[4,3,2-cd]indazol-9-ol | | CAS: | 94636-28-9 | | MF: | C23H31N5O2S | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | 94636-28-9.mol |  |
| | PD 114595 Chemical Properties |
| | PD 114595 Usage And Synthesis |
| Description | PD 114595 is a Benzothiopyrano-indazole cpd. Cl-958, PD 121373, and PD 114595 belong to a new class of DNA complexers, substituted 2H-[1]benzothiopyrano[4,3,2-cd] indazoles, and are being further developed as antitumor drugs based on their curative properties against murine solid tumor models. The biochemical effects of these drugs on L1210 leukemia cells and their interaction with DNA were studied and compared to clinically used intercalators. The benzothiopyranoindazoles bound to DNA with a relatively high affinity, having intrinsic association constants of between 3 and 4 x 10(5) M-1. | | Uses | PD 114595 is a Benzothiopyrano-indazole compound[1]. | | References | [1] Cole SP. Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell line. Cancer Chemother Pharmacol. 1990;26(4):250-6. DOI:10.1007/BF02897225 |
| | PD 114595 Preparation Products And Raw materials |
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