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Boc-L-Glutamic acid 1-benzyl ester

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Company Name: Capot Chemical Co.,Ltd.
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Products Intro: Product Name:Boc-Glu-OBzl
CAS:30924-93-7
Purity:98%(Min,HPLC) Package:100g;1kg;5kg,10kg,25kg,50kg
Company Name: ATK CHEMICAL COMPANY LIMITED
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Products Intro: Product Name:Boc-Glu-OBzl
CAS:30924-93-7
Purity:98% HPLC Package:5G;10G;25G;50G;100G;250G;1KG
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Products Intro: Product Name:Boc-L-Glutamic acid 1-benzyl ester
CAS:30924-93-7
Purity:99% Package:1KG;1USD
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Products Intro: Product Name:Boc-L-Glutamic acid 1-benzyl ester
CAS:30924-93-7
Company Name: BOC Sciences
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Products Intro: Product Name:Boc-L-glutamic acid-α-benzyl ester
CAS:30924-93-7
Purity:>= 98% (HPLC) Remarks:Reach out to us for more information about custom solutions.

Boc-L-Glutamic acid 1-benzyl ester manufacturers
Boc-L-Glutamic acid 1-benzyl ester Basic information
Product Name:Boc-L-Glutamic acid 1-benzyl ester
Synonyms:N-Boc-D-glutamic acid 1-benzyl ester, 99%;N-(tert-butoxycarbonyl)-L-glutamic acid alpha-benzyl ester;N-(Tert-butoxycarbonyl)-l-glutamic acid 1-be;L-GlutaMic acid, N-[(1,1-diMethylethoxy)carbonyl]-, 1-(phenylMethyl) ester;1-Benzyl N-Boc-L-glutamate N-Boc-L-glutamic Acid 1-Benzyl Ester N-(tert-Butoxycarbonyl)-L-glutamic Acid 1-Benzyl Ester Boc-Glu-OBzl;α-benzyl Nα-(tert-butyloxycarbonyl)-L-glutaMate;N-Boc-L-glutamic Acid α-Benzyl Ester;N-T-BOC-L-GLUTAMIC ACID-A-BENZYL ESTERCR YSTALLINE
CAS:30924-93-7
MF:C17H23NO6
MW:337.37
EINECS:
Product Categories:Glutamic acid [Glu, E];Amino Acid Derivatives;Amino Acids;peptide;Amino Acids (N-Protected);Biochemistry;Boc-Amino Acids;Boc-Amino Acids and Derivative
Mol File:30924-93-7.mol
Boc-L-Glutamic acid 1-benzyl ester Structure
Boc-L-Glutamic acid 1-benzyl ester Chemical Properties
Melting point 95.0 to 99.0 °C
Boiling point 522.6±50.0 °C(Predicted)
density 1+-.0.06 g/cm3(Predicted)
refractive index -30 ° (C=0.7, MeOH)
storage temp. Sealed in dry,Store in freezer, under -20°C
solubility Chloroform (Slightly), Methanol (Slightly)
pka4.48±0.10(Predicted)
form Solid
color White
Optical Rotation-27.1°(C=0.01g/mI, MEOH, 20°C, 589nm)
BRN 2482076
Major Applicationpeptide synthesis
InChIInChI=1S/C17H23NO6/c1-17(2,3)24-16(22)18-13(9-10-14(19)20)15(21)23-11-12-7-5-4-6-8-12/h4-8,13H,9-11H2,1-3H3,(H,18,22)(H,19,20)/t13-/m0/s1
InChIKeyCVZUKWBYQQYBTF-ZDUSSCGKSA-N
SMILESC(OCC1=CC=CC=C1)(=O)[C@H](CCC(O)=O)NC(OC(C)(C)C)=O
CAS DataBase Reference30924-93-7(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29242990
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
Boc-L-Glutamic acid 1-benzyl ester Usage And Synthesis
DescriptionBoc-Glu-OBzl is an amino acid building block. It has been used in the synthesis of peptide-based inhibitors of human caspases and human rhinovirus (HRV) 3C protease that have enzyme inhibitory activity in vitro.
Chemical PropertiesWhite Solid
UsesBoc-L-Glutamic acid 1-benzyl ester is an effective substrate for vitamin K-dependent carboxylase,it is a monopeptide used to study the interaction of nucleic acid bases with peptides.
UsesN-Boc-L-glutamic Acid α-Benzyl Ester is an effective substrate for vitamin K-dependent carboxylase. N-Boc-L-glutamic Acid α-Benzyl Ester is a monopeptide used to study the interaction of nucleic acid bases with peptides.
reaction suitabilityreaction type: Boc solid-phase peptide synthesis
References[1] M GARCIA-CALVO. Inhibition of human caspases by peptide-based and macromolecular inhibitors.[J]. The Journal of Biological Chemistry, 1998, 273 49: 32608-32613. DOI: 10.1074/jbc.273.49.32608
[2] PETER S. DRAGOVICH. Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide StructureActivity Studies[J]. Journal of Medicinal Chemistry, 1998, 41 15: 2819-2834. DOI: 10.1021/jm9800696
Boc-L-Glutamic acid 1-benzyl ester Preparation Products And Raw materials
Preparation ProductsBoc-L-Glutamic acid-->BOC-GLU(OME)-OH
Tag:Boc-L-Glutamic acid 1-benzyl ester(30924-93-7) Related Product Information
1,1'-Carbonyldiimidazole Benzyl benzoate N-Carbobenzyloxyglycine Methyl acrylate L-Glutamic acid Tris(trimethylsilyl)phosphate Trimethoprim Benzyl alcohol Benzyl bromide Fmoc-D-Aspartic acid beta-tert-butyl ester FMOC-SER-OME FMOC-GLU-OALL Glutamic acid Carbonyl iron powder L-Glutamic acid alpha-benzyl ester D(-)-Glutamic acid Boc-L-Glutamic acid BOC-D-GLU-OH